Is Intermittent Fasting Safe for Everyone? A Guide for Patients and Clinicians
- Mohammed A Rashad
- 3 days ago
- 5 min read

Skipping breakfast to shed a few pounds or squeezing all your meals into a six-hour window might sound like a modern health trend, but intermittent fasting has roots stretching back centuries. Today, it’s making headlines not just for weight loss, but for its potential to transform heart health, blood sugar, and more. Yet, behind the buzz, questions linger. Can everyone safely try intermittent fasting, or are there hidden risks that patients and clinicians need to consider?
Recent research has sparked both excitement and debate, with some studies showing impressive improvements in weight, glucose, and cholesterol. But the real story is more nuanced. For people managing diabetes, those on certain medications, or anyone with a history of frailty or eating disorders, the decision to fast isn’t straightforward.
This guide unpacks the latest evidence and offers practical advice, helping you and your healthcare team decide if intermittent fasting is truly the right fit.
Key Takeaways:
What Is Intermittent Fasting and How Does It Work?
Intermittent fasting (IF) is more than just skipping meals. It’s a structured approach to eating that cycles between periods of fasting and eating. Unlike traditional calorie restriction, which focuses on reducing daily intake, intermittent fasting is about when you eat rather than what you eat.
Common Types of Intermittent Fasting
Time-Restricted EatingEating all meals within a set window each day, such as 8 hours eating and 16 hours fasting.
Alternate-Day FastingAlternating between days of normal eating and days where calorie intake is significantly reduced.
5:2 DietEating normally for five days a week and restricting calories to about 500–600 on two non-consecutive days.
Each method has its own appeal, but the underlying principle is the same: giving the body regular breaks from food to potentially trigger metabolic benefits.
Why Cardiometabolic Risk Matters
Cardiometabolic risk refers to the likelihood of developing conditions such as heart disease, stroke, and type 2 diabetes. These risks are influenced by factors including:
Body weight and waist circumference
Blood glucose levels
Blood pressure
Cholesterol and lipid profiles
Managing these markers is crucial for long-term health, especially as rates of obesity and diabetes continue to rise. Even modest improvements in these areas can significantly reduce the risk of serious illness.
What Does the Latest Evidence Say?
Recent studies, including a major review published in The BMJ, have brought intermittent fasting into the spotlight. Here’s what the evidence shows:
Key Findings
Both intermittent fasting and calorie restriction can improve cardiometabolic markers.Participants in studies often saw reductions in weight, improved blood glucose control, and better cholesterol profiles.
Short-term benefits are clear, but long-term effects remain uncertain.Most research has followed participants for only a few months, making it difficult to draw conclusions about sustained benefits or risks.
Results are heterogeneous.Different fasting protocols, participant characteristics, and study designs mean that not everyone will experience the same outcomes.
What This Means for You
While intermittent fasting can be effective for some, it’s not a one-size-fits-all solution. The improvements in weight, blood sugar, and cholesterol are promising, but more high-quality, long-term studies are needed to confirm these effects and understand who benefits most.
Who Should Be Cautious with Intermittent Fasting?
Intermittent fasting is not suitable for everyone. Certain groups should approach fasting with caution or avoid it altogether.
Groups Requiring Special Consideration
People with diabetes, especially those on insulin or sulphonylureasFasting can increase the risk of hypoglycaemia (low blood sugar), which can be dangerous.
Older adults or those with frailtyRestricting food intake may lead to malnutrition, muscle loss, or dehydration.
Pregnant or breastfeeding womenNutritional needs are higher during these periods, and fasting may not provide adequate energy or nutrients.
Individuals with a history of eating disordersFasting can trigger unhealthy behaviours or relapse.
Children and adolescentsGrowth and development require consistent nutrition.
When to Consult a Healthcare Professional
If you fall into any of these categories, it’s essential to speak with your GP, pharmacist, or a registered dietitian before starting any fasting regimen. Personalised advice ensures your safety and helps you make informed decisions.
How to Choose the Right Approach
The best dietary approach is the one you can sustain safely. Here’s how to personalise your plan:
1. Assess Your Health Status
Review your medical history and current medications.
Consider your lifestyle, work schedule, and family commitments.
2. Set Realistic Goals
Focus on overall health, not just weight loss.
Aim for gradual, sustainable changes.
3. Choose a Method That Fits
If you prefer structure, time-restricted eating may be easier to follow.
If flexibility is important, the 5:2 diet could be a better fit.
4. Monitor Your Progress
Track changes in weight, blood pressure, and blood glucose (if relevant).
Watch for symptoms such as dizziness, fatigue, or mood changes.
5. Adjust as Needed
If you experience side effects or find the regimen unsustainable, consider alternative approaches.
Regular check-ins with your healthcare team can help you stay on track.
Safety First: What to Monitor
Focusing solely on weight loss can be misleading. Effective monitoring includes:
Key Areas to Watch
HypoglycaemiaEspecially important for people with diabetes. Symptoms include sweating, confusion, shakiness, and fainting.
DehydrationFasting can reduce fluid intake. Ensure you drink enough water throughout the day.
Nutrient DeficiencyRestricting food can lead to inadequate intake of vitamins and minerals.
AdherenceConsistency is key. If you find yourself frequently breaking the fast or feeling unwell, reassess your approach.
Practical Tips for Safe Fasting
Start with shorter fasting periods and gradually increase as tolerated.
Avoid fasting during periods of illness or high physical demand.
Include nutrient-dense foods during eating windows.
Stay hydrated with water, herbal teas, or other non-caloric beverages.
Seek support from healthcare professionals for guidance and monitoring.
Practical Advice for Patients and Clinicians
For Patients
Be honest about your medical history and lifestyle.
Ask questions if you’re unsure about the safety or suitability of fasting.
Listen to your body and stop fasting if you feel unwell.
For Clinicians
Assess each patient individually.
Review medications that may need adjustment during fasting.
Provide clear guidance on what to monitor and when to seek help.
Encourage regular follow-up to address challenges and celebrate successes.
Conclusion
Intermittent fasting offers promising benefits for weight, blood sugar, and heart health, but it’s not suitable for everyone. The key is to choose an approach that fits your health needs and lifestyle, with support from your healthcare team. By focusing on safety, personalisation, and ongoing monitoring, you can make informed choices for your long-term wellbeing.
For advice and support, contact The Medicines Management Team today. Stay informed, stay healthy, and remember: your health journey is unique.
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